Feviprant Powder CAS .872365-14-5 99% Min
Khoom npe: Fevipiprant Powder
CAS Nr .: 872365-14-5
Cov mis mos molecular: C₂₀H₂₃ClFNO
Molecular Luj: 347.86
Purity: 99.0%
Peev xwm: 100kgs ib hlis
Source: hluavtaws
Purity (HPLC) >98.0%
Qhov chaw ntawm Keeb Kwm: Tuam Tshoj Yinherb-Lab
Packing: Raws li tus neeg siv khoom xav tau
Yam tsawg kawg nkaus Order Quantity: 1kg
Cia: Khaws rau hauv qhov chaw txias & qhuav, Khaws kom deb ntawm lub teeb muaj zog thiab cua sov rau 2 xyoos
Hauj lwm lawm
Xi'an Yinherb Bio-Tech Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm fevipiprant hmoov cas.872365-14-5 99% min hauv Suav teb, kuj txhawb kev pabcuam customized. Zoo siab txais tos mus yuav bulk fevipiprant hmoov cas.872365-14-5 99% min muag ntawm no los ntawm peb lub hoobkas. Cov khoom zoo thiab tus nqi tsim nyog muaj.
Kev Tshawb Fawb Kev Tshawb Fawb ntawm Nootropics & peptide hauv Suav teb
Yinherb Lab yog lub chaw tshawb fawb kev tshaj lij hauv Suav teb, tau tsom mus rau Cov Khoom Noj Khoom Haus, Nootropics thiab Peptide raw cov ntaub ntawv tshawb fawb thiab tsim tawm hauv kev lag luam no rau ntau tshaj 10 xyoo nrog kev ruaj khov zoo thiab muaj koob npe nrov, peb tuaj yeem muab txhua qhov kev xeem batch, suav nrog COA, HPLC thiab NMR. Kuv ntseeg tias peb yuav tsum ua haujlwm zoo yav tom ntej.
Yinherb Lab High Quality Fevipiprant Powder CAS{0}}% Min
Khoom npe: Fevipiprant Powder
Tshuaj npe(R)-2-(2-Chlorophenyl)-1-(3-fluorophenyl)-3-(piperidin-1-yl)propan-1-ol
CAS Nr: 872365-14-5
Molecular Formula: C₂₀H₂₃ClFNO
Molecular Luj: ~347.86
Purity Standard: Ntau dua lossis sib npaug li 99% (ua raws li cov qauv tshuaj USP / BP / GMP)
Qhov tshwm sim: Dawb rau tawm -dawb crystalline hmoov
Solubility: me ntsis soluble hauv dej; Soluble hauv cov kuab tshuaj organic xws li ethanol, DMSO, thiab methanol
Melting Point: Kwv yees li 128-132℃(nws txawv me ntsis los ntawm purity)
Kev ruaj ntseg: ruaj khov raws li kev pom zoo cia; rhiab heev rau qhov kub thiab txias
Fevipiprant Powder yog dab tsi?
Fevipiprant hmoov yog ib qho siab -purity (Ntau dua lossis sib npaug li 99%) kws tshuaj API, ib qho kev xaiv CRTh2 antagonist feem ntau qhia rau kev kho mob hawb pob. Nws nthuav tawm cov khoom tshwj xeeb physicochemical, zoo-txhais kev ua tshuaj kho mob, thiab cov kev cai tswj kev ua tau zoo, nrog rau cov kev siv dav dav rau kev siv kab mob.
Fevipiprant yog CRTh2 antagonist (feem ntau yog rau qhov mob / mob hawb pob) nrog cov muaj peev xwm tshwm sim hauv inflammatory- cuam tshuam cov plaub hau, thaum cov plaub hau plam cov khoom xyaw tsom rau androgen receptors, plaub hau follicle loj hlob, los yog cov ntshav txaus- cov lus no qhia txog qhov sib txawv tseem ceeb hauv kev siv tshuab, kev siv, thiab kev nyab xeeb.
Fevipiprant Powder Mechanism of Action
Hom phiaj ua
Xaiv khi rau CRTh2 receptors (qhia rau Th2 hlwb, eosinophils, basophils, thiab mast hlwb) nrog siab affinity (Ki=0.4 nM rau tib neeg CRTh2)
Thaiv kev khi ntawm prostaglandin D2 (PGD2) rau CRTh2, qhov tseem ceeb ligand mediating hom 2 mob
Pharmacological teebmeem
Inhibits recruitment thiab activation ntawm Th2 hlwb, eosinophils, thiab basophils nyob rau hauv inflammatory sites
Txo kev tso tawm ntawm pro-inflammatory cytokines (IL-4, IL-5, IL-13) thiab chemokines
Alleviates cov hlab ntsws o, hyperresponsiveness, thiab mucus hypersecretion hauv hawb pob
Modulates inflammatory cov lus teb tsis cuam tshuam rau lwm yam prostaglandin receptors
Fevipiprant Powder Applications & Formulation Guidelines
Kev tsim kho cov plaub hau poob: Nws yog cov khoom siv tshuaj nquag (API) rau ntau yam tshuaj pleev plaub hau. Cov neeg tsim khoom muab nws nrog cov khoom ntxiv xws li ethanol thiab propylene glycol los tsim cov tshuaj xws li 2% thiab 5% minoxidil daws, foams, gels, thiab tinctures. Cov khoom no tau siv dav hauv kev kho mob androgenetic alopecia thiab alopecia areata ntawm cov txiv neej thiab poj niam.
Tsim cov tshuaj antihypertensive: Hauv kev lag luam kws tshuaj, nws ua haujlwm raws li cov khoom siv raw rau cov tshuaj tiv thaiv qhov ncauj. Nws yog tsuas yog siv rau kev kho mob ntshav siab hnyav uas muaj cov tsos mob lossis ua rau lub cev tsis zoo, txawm tias nws siv qhov ncauj muaj qhov cuam tshuam loj heev thiab yuav tsum tau saib xyuas kev kho mob nruj.
Cov lus sib piv: Fevipiprant Powder vs. Zoo sib xws cov plaub hau kev kho mob cov khoom xyaw
| Sib piv Dimension | Fevipirant hmoov | Minoxidil hmoov | Finasteride hmoov | Ketoconazole hmoov | Pom Palmetto Extract Powder(Natural Ingredients) |
|---|---|---|---|---|---|
| Core Mechanism | Xaiv CRth2 antagonist; inhibits hom 2 o (blocks PGD2-CRTh2 khi); Tej zaum yuav txo cov follicle o hauv alopecia areata / eczema-hais txog cov plaub hau poob | Potassium channel opener; prolongs cov plaub hau follicle anagen theem; txhawb nqa angiogenesis; thim rov qab follicle miniaturization | 5 -reductase inhibitor; thaiv kev hloov pauv ntawm testosterone rau DHT (androgen receptor antagonist) | Antifungal (inhibits Malassezia); txo cov tawv nqaij o; me me los tiv thaiv-androgenic nyhuv | Ntuj 5 -reductase inhibitor; blocks DHT khi rau follicle receptors; anti- mob |
| Thawj qhov taw qhia | Asthma (nruab nrab-rau-mob eosinophilic); tawm rau inflammatory plaub hau poob (tawm-label) | Androgenetic alopecia (txiv neej / poj niam); alopecia areata (adjunctive) | Androgenetic alopecia (txiv neej-tsuas); benign prostatic hyperplasia (BPH) | Dandruff / seborrheic dermatitis; adjunct rau inflammatory plaub hau poob | Androgenetic alopecia (mob-rau- nruab nrab); natural lwm txoj rau finasteride |
| Cov plaub hau poob hom phiaj | Inflammatory-cov plaub hau tsis sib haum xeeb (alopecia areata, seborrheic alopecia) | Androgenetic alopecia; diffuse plaub hau thinning | Androgenetic alopecia (hormonal{0}}tsav) | Inflammatory/ fungal- cuam tshuam cov plaub hau poob; txhawb nqa kev noj qab haus huv ntawm tawv taub hau | Androgenetic alopecia (mob hormonal-tsav) |
| Kev siv tshuaj | Qhov ncauj (cov ntsiav tshuaj / ntsiav tshuaj); muaj peev xwm tshuaj formulations (R & D theem) | Tshuaj pleev ib ce (cov tshuaj, foams, gels); qhov ncauj (antihypertensive, tawm - daim ntawv lo rau cov plaub hau poob) | Qhov ncauj (cov ntsiav tshuaj); tshuaj (formulations in development) | tshuaj pleev (sampoos, cream); qhov ncauj (antifungal, tsis tshua muaj rau cov plaub hau poob) | Qhov ncauj (cov tshuaj ntxiv); tshuaj pleev (serums, tshuaj zawv plaub hau) |
| Purity Standard | Ntau dua lossis sib npaug li 99% ( qib tshuaj, USP / BP / EP) | Ntau dua lossis sib npaug li 99% (qib tshuaj, USP / BP) | Ntau dua lossis sib npaug li 99% (qib tshuaj, USP / BP) | Ntau dua lossis sib npaug li 98% (qib tshuaj / tshuaj pleev ib ce) | Ntau dua lossis sib npaug rau 45% fatty acids (qib tshuaj pleev ib ce / nutraceutical) |
| Yam Tseem Ceeb Kev Nyab Xeeb | Cov tawv nqaij me me / qhov muag khaus; tsawg mob toxicity; tsis muaj tshuaj lom neeg yug menyuam (preclinical) | Tshuaj: tawv taub hau irritation, dryness; Qhov ncauj: Hypotension, tachycardia, kua retention | Qhov ncauj: kev phiv los ntawm kev sib deev (erectile kawg, libido poob); contraindicated nyob rau hauv cov poj niam cev xeeb tub | Tshuaj: mob tawv taub hau me ntsis; Qhov ncauj: Hepatotoxicity (tsis tshua muaj) | Mob plab hnyuv me (qhov ncauj); tsis muaj kev pheej hmoo loj |
| Lub Sijhawm Ua Haujlwm Zoo | 3-6 lub hlis (cov ntaub ntawv tshiab rau cov plaub hau poob); qeeb pib rau cov mob inflammatory | 3-6 lub hlis (pom cov plaub hau regrowth); 12 lub hlis rau cov nyhuv siab tshaj plaws | 3-6 lub hlis (hais plaub hau stabilization); 6-12 lub hlis rau regrowth | 1-2 lub hlis (kev txhim kho tawv taub hau); adjunctive nyhuv ntawm cov plaub hau poob ntau tshaj 3+ hli | 3-6 lub hlis (mob plaub hau tsis muaj zog); qeeb dua finasteride/minoxidil |
| Tshwj xeeb zoo | Targets o (tsis xav tau rau inflammatory alopecia); tsis muaj hormonal cuam tshuam | Poj niam los txiv neej- nruab nrab ( nyab xeeb rau txiv neej / poj niam); Cov pov thawj regrowth rau androgenetic alopecia | Muaj zog hormonal thaiv; high efficiency rau txiv neej qauv baldness | Muab tshuaj tua kab mob + tshuaj tiv thaiv- mob; txhim kho tawv taub hau | Ntuj, tsis muaj kab mob hormonal phiv; haum rau cov mob me |
| Kev txwv | Txwv cov ntaub ntawv kho mob rau cov plaub hau poob; feem ntau sim siv | Yuav tsum tau siv tshuaj pleev ib ce txhua hnub; muaj peev xwm ua kom tawv nqaij tawv nqaij; tsis muaj kev cuam tshuam rau qhov hnyav baldness | Txiv neej-tsuas yog siv; kev mob tshwm sim ntawm kev sib deev; teratogenic txaus ntshai rau cov poj niam | Tsis yog ib leeg kho plaub hau poob; antifungal- tshwj xeeb ua | Kev ua haujlwm qis dua finasteride / minoxidil; inconsistent zoo nyob rau hauv tej yam ntuj tso khoom |
Cov khoom lag luam ntsig txog
Tshwj xeeb hauv Fevipiprant, Minoxidil, Fluridil, SM04554, Clascoterone CB-03-01, -estradiol, WAY316606, thiab lwm yam.
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Cov ntawv pov thawj
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Yinherb Lab nrhiav tau nyob rau hauv 2009, tau mob siab rau rau biotechnology teb rau ntau tshaj kaum xyoo. Niaj hnub no, nws tau tsim ib qho kev txhim kho kev ua haujlwm nrog "R & D + ntau lawm" ua ib qho kev sib koom ua ke. Thiab ib txwm ua raws li cov kev lag luam tseem ceeb ntawm "Quality First, Service Second, Price Third".
Peb qhov chaw nyob
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Cim npe nrov: fevipirant hmoov cas.872365-14-5 99% min, Tuam Tshoj fevipiprant hmoov cas.872365-14-5 99% min manufacturers, lwm tus neeg, Hoobkas
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