SM04554 hmoov CAS.1360540-81-3 99% Min
Khoom npe: SM04554 Powder
CAS Nr .1360540 - 81 - 3
Cov mis mos molecular: C₁₈H₁₆O₄
Molecular Luj: 296.32
Purity: 99.0%
Peev xwm: 100kgs ib hlis
Source: hluavtaws
Purity (HPLC) >98.0%
Qhov chaw ntawm Keeb Kwm: Tuam Tshoj Yinherb-Lab
Packing: Raws li tus neeg siv khoom xav tau
Yam tsawg kawg nkaus Order Quantity: 1kg
Cia: Khaws rau hauv qhov chaw txias & qhuav, Khaws kom deb ntawm lub teeb muaj zog thiab cua sov rau 2 xyoos
Hauj lwm lawm
Xi'an Yinherb Bio-Tech Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm sm04554 hmoov cas.1360540-81-3 99% min hauv Suav teb, kuj txhawb kev pabcuam customized. Txais tos mus yuav bulk sm04554 hmoov cas.1360540-81-3 99% min rau muag ntawm no los ntawm peb lub hoobkas. Cov khoom zoo thiab tus nqi tsim nyog muaj.
Kev Tshawb Fawb Kev Tshawb Fawb ntawm Nootropics & peptide hauv Suav teb
Yinherb Lab yog lub chaw tshawb fawb kev tshaj lij hauv Suav teb, tau tsom mus rau Cov Khoom Noj Khoom Haus, Nootropics thiab Peptide raw cov ntaub ntawv tshawb fawb thiab tsim tawm hauv kev lag luam no rau ntau tshaj 10 xyoo nrog kev ruaj khov zoo thiab muaj koob npe nrov, peb tuaj yeem muab txhua qhov kev xeem batch, suav nrog COA, HPLC thiab NMR. Kuv ntseeg tias peb yuav tsum ua haujlwm zoo yav tom ntej.
Yinherb Lab High Quality SM04554 Powder CAS.1360540-81-3 99% Min
Khoom npe: SM04554 Powder
Tshuaj npe(E)-3-(4-Hydroxyphenyl)-2-(4-methoxyphenyl)acrylonitrile
CAS Nr: 1360540-81-3
Molecular Formula: C₁₈H₁₆O₄
Molecular Luj: 296.32
Cov tshuaj: Wnt signaling pathway activator (GSK-3 inhibitor)
Purity Standard: Ntau dua lossis sib npaug li 99% (qib tshuaj / tshuaj pleev ib ce, txheeb xyuas los ntawm HPLC / NMR)
Qhov tshwm sim: Dawb crystalline hmoov, tsw ntxhiab
SolubilitySoluble hauv ethanol, chloroform, propylene glycol, thiab ethylenediamine; me ntsis soluble hauv diethyl ether; ib nrab soluble hauv dej
Kev ruaj ntseg: ruaj khov raws li kev pom zoo cia; rhiab heev rau oxidation muaj zog, huab pH (＜5 lossis ＞8), thiab kub siab
Melting Point: Kwv yees li 168-172℃(nws txawv me ntsis ntawm purity)
Log P (Octanol{0}}Dej faib Coefficient)Qhov ntsuas kub: ~ 3.8 (25℃pH 7.4)
SM04554 Powder yog dab tsi?
SM04554 Powder yog cov hmoov dawb dawb uas yog tsim los kho androgenetic alopecia, thiab nws kuj muaj peev xwm kho cov ntaub so ntswg.
Txawm hais tias nws txoj kev loj hlob rau kev kho plaub hau tau raug tshem tawm, nws tseem nyiam mloog vim nws qhov tshwj xeeb ntawm kev ua haujlwm.
SM04554 Powder kho cov plaub hau poob los ntawm anon-hormonal Wnt signaling pathway activation mechanism, tsom lub hauv paus ntawm follicle miniaturization hauv androgenetic alopecia yam tsis muaj kev cuam tshuam cov tshuaj hormones.
SM04554 Powder Mechanism of Action
GSK-3 Inhibition (Lub Hom Phiaj Tseem Ceeb)
SM04554 tshwj xeeb inhibits glycogen synthase kinase-3 (GSK-3), ib qho enzyme uas ib txwm suppresses Wnt signaling pathway.Blocking GSK-3 tshem tawm qhov "brake" ntawm Wnt kev ua, reactivating txoj hauv kev hauv cov plaub hau follicle hlwb.
Wnt Pathway Activation (Follicle Growth Driver)
Txoj hauv kev Wnt yog qhov tseem ceeb rau kev loj hlob ntawm cov plaub hau follicle thiab cycling.Activated Wnt signaling pib thiab txuas rau anagen (loj hlob) theem ntawm cov plaub hau voj voog, tiv thaiv ntxov ntxov nkag mus rau hauv telogen (so) theem.
Reverses Follicle Miniaturization
Nyob rau hauv androgenetic alopecia, Wnt txoj kev ua tsis muaj zog nyob rau lub sij hawm, ua rau cov follicle loj me me (thinning plaub hau).
Stimulates Progenitor Cell Differentiation
Nws induces dermal progenitor cells (cov plaub hau follicle qia hlwb) kom sib txawv rau hauv cov plaub hau bulge cells.Qhov no txhawb kev tsim cov hauv paus plaub hau tshiab thiab kho cov plaub hau puas, txhim kho tag nrho cov plaub hau ntom.
SM04554 Powder Applications & Formulation Guidelines
Kev kho plaub hau: Nws yog tsuas yog siv los ua cov khoom siv raw rau cov tshuaj pleev ib ce los tiv thaiv- cov khoom siv plaub hau los tsim kev npaj xws li cov tshuaj pleev xim thiab cov tshuaj pleev xim rau androgenetic alopecia. Nws tuaj yeem kho cov hauv paus plaub hau puas thiab txhawb cov plaub hau regrowth. Txawm li cas los xij, nws yuav tsum raug sau tseg tias nws tus tsim tawm, Biosplice Therapeutics (yav tas los Samumed), tau tso tseg txoj kev loj hlob ywj pheej rau kev kho plaub hau thiab tab tom tshawb nrhiav kev tso cai sab nraud.
Cov ntaub so ntswg kho teb: Ntxiv nrog rau kev kho plaub hau, cov hmoov no kuj muaj peev xwm siv tau rau hauv cov ntaub so ntswg kho thiab rov tsim dua tshiab. Nws tuaj yeem txhawb kev loj hlob thiab kev sib txawv ntawm osteoblasts, txhim kho lub peev xwm kho chondrocytes, thiab tseem cuam tshuam cov ntaub so ntswg puas los ntawm cov tshuaj tiv thaiv inflammatory. Nws muaj daim ntawv thov kev cia siab hauv kev kho pob txha pob txha, txhim kho osteoarthritis thiab kho qhov txhab ntawm daim tawv nqaij.
Cov lus sib piv: Cov khoom siv kho plaub hau zoo sib xws
| Sib piv Dimension | Fluridil hmoov | Fevipirant hmoov | Minoxidil hmoov | Finasteride hmoov |
|---|---|---|---|---|
| Core Mechanism | Tsis yog -steroidal anti-androgen; blocks DHT khi rau follicle receptors (tsis muaj kev hloov pauv tshuaj hormones) | CRTh2 antagonist; inhibits hom 2 o (lub hom phiaj inflammatory plaub hau poob) | Potassium channel opener; prolongs anagen theem; txhawb nqa angiogenesis | 5 -reductase inhibitor; blocks testosterone → DHT conversion |
| Thawj qhov taw qhia | Androgenetic alopecia (txiv neej / poj niam); hormonal -tsav plaub hau thinning | Asthma (thawj); tawm - daim ntawv lo rau inflammatory alopecia (zoneta, seborrheic) | Androgenetic alopecia (txiv neej / poj niam); diffuse nyias | Txiv neej androgenetic alopecia; benign prostatic hyperplasia (BPH) |
| Cov plaub hau poob hom phiaj | Hormonal{0}}tsav (androgenetic) | Inflammatory-kuaj kho | Androgenetic + diffuse thinning | Hormonal-tsav (txiv neej- tshwj xeeb) |
| Kev siv tshuaj | Tshuaj pleev ib ce (serums, lotions) | Qhov ncauj (cov ntsiav tshuaj); tshuaj (R & D theem) | Tshuaj pleev ib ce (kev daws / ua npuas ncauj); qhov ncauj (antihypertensive, tawm -label) | Qhov ncauj (cov ntsiav tshuaj); tshuaj (hauv kev loj hlob) |
| Purity Standard | Ntau dua lossis sib npaug li 98% ( qib tshuaj / tshuaj pleev ib ce) | Ntau dua lossis sib npaug li 99% ( qib tshuaj, USP / BP / EP) | Ntau dua lossis sib npaug li 99% (qib tshuaj, USP / BP) | Ntau dua lossis sib npaug li 99% (qib tshuaj, USP / BP) |
| Yam Tseem Ceeb Kev Nyab Xeeb | khaus tawv taub hau me ntsis (tsis tshua muaj); tsis muaj kab mob/hormonal phiv | Cov tawv nqaij mos / qhov muag khaus; tsawg mob toxicity; tsis muaj kev pheej hmoo ntawm kev yug menyuam (preclinical) | Tshuaj: tawv taub hau dryness/irritation; Qhov ncauj: Hypotension, tachycardia | Qhov ncauj: kev phiv los ntawm kev sib deev; teratogenic (cov poj niam muaj hnub nyoog muaj menyuam) |
| Lub Sijhawm Ua Haujlwm Zoo | 3-6 lub hlis (stabilization); 6-9 lub hlis (mob regrowth) | 3-6 lub hlis (cov ntaub ntawv poob plaub hau tshiab); qeeb rau o | 3-6 lub hlis (regrowth); 12 lub hlis (max effect) | 3-6 lub hlis (stabilization); 6-12 lub hlis (kev loj hlob) |
| Tshwj xeeb zoo | Tsis yog -hormonal; nyab xeeb rau txiv neej / poj niam; tsis muaj kev mob tshwm sim | Cov hom phiaj tsis xav tau (inflammatory alopecia); tsis muaj hormonal cuam tshuam | Poj niam txiv neej- nruab nrab; pov thawj regrowth; dav muaj | Muaj zog hormonal thaiv; high efficiency rau txiv neej qauv baldness |
| Kev txwv | Kev ua haujlwm me me regrowth; tsawg mainstream dua minoxidil/finasteride | Txwv cov ntaub ntawv kho mob plaub hau poob; kev sim siv rau alopecia | Yuav tsum tau thov txhua hnub; tsis muaj kev cuam tshuam rau qhov hnyav baldness | Txiv neej-tsuas yog siv; teratogenic txaus ntshai; kev mob tshwm sim ntawm kev sib deev |
Cov khoom lag luam ntsig txog
Tshwj xeeb hauv Fevipiprant, Minoxidil, Fluridil, SM04554, Clascoterone CB-03-01, -estradiol, WAY316606, thiab lwm yam.
 |
 |
Cov ntawv pov thawj
FDA
Halal
ISO 9001 Cov
Kosher
Kev Tshawb Fawb Tshaj Tawm
SGS
Yinherb Lab nrhiav tau nyob rau hauv 2009, tau mob siab rau rau biotechnology teb rau ntau tshaj kaum xyoo. Niaj hnub no, nws tau tsim ib qho kev txhim kho kev ua haujlwm nrog "R & D + ntau lawm" ua ib qho kev sib koom ua ke. Thiab ib txwm ua raws li cov kev lag luam tseem ceeb ntawm "Quality First, Service Second, Price Third".
Peb qhov chaw nyob
No.3, Daqing rd, Hi-tech zone, Xi'an, Suav teb.
Xov tooj
+8618681897250
E -mail
Cim npe nrov: sm04554 hmoov cas.1360540-81-3 99% min, Tuam Tshoj sm04554 hmoov cas.1360540-81-3 99% min manufacturers, lwm tus neeg, Hoobkas
Xa kev nug
Koj Tseem Yuav Zoo Li
