Clascoterone (CB-03-01) hmoov CAS{1}}% Min
Khoom npe: Clascoterone (CB-03-01) hmoov
CAS Nr .: 19608-29-8
Cov mis mos molecular: C₁₂H₁₁NO₄
Molecular Luj: 233.22
Purity: 99.0%
Peev xwm: 100kgs ib hlis
Source: hluavtaws
Purity (HPLC) >98.0%
Qhov chaw ntawm Keeb Kwm: Tuam Tshoj Yinherb-Lab
Packing: Raws li tus neeg siv khoom xav tau
Yam tsawg kawg nkaus Order Quantity: 1kg
Cia: Khaws rau hauv qhov chaw txias & qhuav, Khaws kom deb ntawm lub teeb muaj zog thiab cua sov rau 2 xyoos
Hauj lwm lawm
Xi'an Yinherb Bio-Tech Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm clascoterone (cb-03-01) hmoov cas.19608-29-8 99% min hauv Suav teb, kuj txhawb kev pabcuam customized. Txais tos muas bulk clascoterone (cb-03-01) hmoov cas.19608-29-8 99% min rau muag ntawm no los ntawm peb lub hoobkas. Cov khoom zoo thiab tus nqi tsim nyog muaj.
Kev Tshawb Fawb Kev Tshawb Fawb ntawm Nootropics & peptide hauv Suav teb
Yinherb Lab yog lub chaw tshawb fawb kev tshaj lij hauv Suav teb, tau tsom mus rau Cov Khoom Noj Khoom Haus, Nootropics thiab Peptide raw cov ntaub ntawv tshawb fawb thiab tsim tawm hauv kev lag luam no rau ntau tshaj 10 xyoo nrog kev ruaj khov zoo thiab muaj koob npe nrov, peb tuaj yeem muab txhua qhov kev xeem batch, suav nrog COA, HPLC thiab NMR. Kuv ntseeg tias peb yuav tsum ua haujlwm zoo yav tom ntej.
Yinherb Lab High Quality Clascoterone (CB-03-01) hmoov CAS.19608-29-8 99% Min
Khoom npe: Clascoterone (CB-03-01)
Tshuaj npe: 4'-Cyano-3-(4-hydroxy-3-methoxyphenyl)-2-methylprop-2-enoic acid
CAS Nr: 1242156-59-7
Molecular Formula: C₁₂H₁₁NO₄
Molecular Luj: ~233.22
Cov tshuaj: Tsis yog -steroidal androgen receptor (AR) antagonist
Purity Standard: Ntau dua lossis sib npaug li 99% (qib tshuaj, USP / BP / EP raws cai)
Purity: Ntau dua lossis sib npaug li 99.0% (HPLC kev soj ntsuam)
Ib leeg Impurity: Tsawg dua lossis sib npaug li 0.3% (tus neeg tsis huv, HPLC)
Tag nrho cov impurities: Tsawg dua lossis sib npaug li 1.0% (HPLC)
Poob rau ziab: Tsawg dua lossis sib npaug li 0.5% (105 degree, 2 teev)
Residue ntawm Ignition: Tsawg dua lossis sib npaug li 0.1%
Hnyav Hlau: Tsawg dua lossis sib npaug li 10 ppm
Solvent Residue: Ua tau raws li ICH Q3C cov lus qhia
Qhov tshwm sim: Dawb rau tawm -dawb crystalline hmoov, tsw tsw
Solubility: me ntsis soluble hauv dej (<1 mg/mL at 25°C); soluble in ethanol (20–30 mg/mL), DMSO (≥50 mg/mL), propylene glycol (15–25 mg/mL)
Kev ruaj ntseg: ruaj khov nyob rau hauv txias, qhuav; degraded los ntawm muaj zog acids, bases, thiab UV teeb; hydrolysis-nrhiav hauv siab- ib puag ncig noo noo
Clascoterone (CB-03-01) hmoov yog dab tsi?
Clascoterone (CB-03-01) hmoov yog ib qho uas tsis yog-steroidal androgen receptor inhibitor (CAS 1242156-59-7) nrog ob daim ntawv thov hauv pob txuv thiab androgenetic alopecia, featuring ib qho tshwj xeeb hauv zos anti-androgen mechanism thiab kev ruaj ntseg profile.
Clascoterone kho cov plaub hau poob los ntawm ahauv zos, tsis yog -steroidal androgen receptor (AR) antagonism mechanism- nws thaiv DHT qhov teeb meem cuam tshuam rau cov hauv paus plaub hau yam tsis muaj kev cuam tshuam cov tshuaj hormones.
Clascoterone tsom rau androgen receptors (AR) ntawm cov plaub hau follicle dermal papilla hlwb, qhov chaw tshwj xeeb uas DHT (dihydrotestosterone) ua rau cov follicles puas.
Clascoterone (CB-03-01) Powder Mechanism of Action
Rau Androgenetic Alopecia
Hauv zos Androgen Receptor Blockade: khi xaiv rau androgen receptors ntawm cov plaub hau follicle dermal papilla hlwb.
DHT Kev tawm tsam: Tiv thaiv DHT los ntawm kev txuas mus rau follicle receptors, halting miniaturization thiab khaws cia cov plaub hau kev loj hlob.
Tsis muaj kev cuam tshuam rau cov tshuaj hormones: Tsis txo qis DHT ntau lawm (tsis zoo li finasteride) lossis hloov cov tshuaj hormones hauv lub cev, zam kev mob tshwm sim.
Rau pob txuv Vulgaris
Sebocyte Activity Inhibition: Blocks androgen receptors nyob rau hauv cov qog sebaceous, txo sebum (roj) ntau lawm.
Los tiv thaiv -Inflammatory Effect: Txhawb nqa pro-inflammatory cytokines (IL-6, TNF- ) hauv daim tawv nqaij, txo cov pob txuv thiab liab.
Clascoterone (CB-03-01) Powder Applications & Formulation Guidelines
Cov ntsiab lus tseem ceeb
Cov plaub hau poob: Cov tshuaj pleev ib ce rau androgenetic alopecia (txiv neej / poj niam qauv plaub hau poob, me me - rau - nruab nrab).
Pob txuv: Tshuaj pleev ib ce/gels rau lub ntsej muag pob txuv vulgaris (FDA- pom zoo raws li lub npe Winlevi®).
Formulation Hom & Compatibility
Cov plaub hau poob Formulations: Serums, lotions (concentration 1–2%), blended with ethanol, propylene glycol, and penetration enhancers.
Pob txuv Formulations: Creams (1% concentration), ua ke nrog moisturizers (panthenol, glycerin) thiab me me preservatives (phenoxyethanol).
Compatible Excipients: Microcrystalline cellulose, HPMC, croscarmellose sodium, magnesium stearate (rau cov khoom formulations); ethanol, propylene glycol, glycerin (rau cov kua tshuaj pleev ib ce).
Cov khoom tsis sib xws: Muaj zog acids/bases, oxidizing agents, siab - cawv formulations (rau rhiab tawv nqaij).
Cov lus sib piv: Cov khoom siv kho plaub hau zoo sib xws
| Feature | Clascoterone (CB-03-01) | Fluridil | Finasteride | Minoxidil |
|---|---|---|---|---|
| Mechanism | Hauv zos AR antagonist (blocks DHT-follicle khi) | Tsis yog -steroidal AR antagonist | 5 -reductase inhibitor (txo DHT) | Potassium channel opener (boosts ntshav txaus) |
| Poj niam los txiv neej Suitability | Txiv neej / poj niam (muaj kev nyab xeeb rau txhua tus) | Txiv neej/pojniam | Txiv neej-tsuas yog (teratogenic rau cov poj niam) | Txiv neej/pojniam |
| Cov teebmeem tshwm sim | Tsis muaj | Tsis muaj | Kev phiv los ntawm kev sib deev (libido poob, ED) | Hypotension (qhov ncauj); tawv taub hau irritation (tshuaj pleev) |
| Kev Siv Tseem Ceeb Ntxiv | Pob txuv vulgaris | Tsis muaj | Benign prostatic hyperplasia | Ntshav siab |
Cov khoom muaj feem xyuam
Tshwj xeeb hauv Fevipiprant, Minoxidil, Fluridil, SM04554, Clascoterone CB-03-01, -estradiol, WAY316606, thiab lwm yam.
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Yinherb Lab nrhiav tau nyob rau hauv 2009, tau mob siab rau rau biotechnology teb rau ntau tshaj kaum xyoo. Niaj hnub no, nws tau tsim ib qho kev txhim kho kev ua haujlwm nrog "R & D + ntau lawm" ua ib qho kev sib koom ua ke. Thiab ib txwm ua raws li cov kev lag luam tseem ceeb ntawm "Quality First, Service Second, Price Third".
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