Eptifibatide Powder CAS. 188627-80-7 99% Purity Min factory
Eptifibatide Powder CAS. 188627-80-7 99% Purity Min best
Eptifibatide Powder CAS. 188627-80-7 99% Purity Min high quality
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Eptifibatide Powder CAS . 188627-80-7 99% Purity Min
Lub npe Askiv: Eptifibatide hmoov
CAS Nr .: 188627-80-7
Molecular Luj: 700.78g / mol
Molecular Formula: C₂₈H₄₃N₁₁O₉S
Qhov tsos: dawb hmoov
tsw: no
Stability: ruaj khov
MSDS thiab COA: muaj rau koj siv
Peev xwm: 500g ib hlis
Qhov tsos: dawb hmoov
Source: hluavtaws
Purity (HPLC) >98.0%
Qhov chaw ntawm Keeb Kwm: Tuam Tshoj Yinherb-Lab
Packing: Raws li tus neeg siv khoom xav tau
Yam tsawg kawg nkaus Order Quantity: 10g
Cia: Khaws rau hauv qhov chaw txias & qhuav, Khaws kom deb ntawm lub teeb muaj zog thiab cua sov rau 2 xyoos
Hauj lwm lawm
Xi'an Yinherb Bio-Tech Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm eptifibatide hmoov cas. 188627-80-7 99% purity min hauv Suav teb, kuj txhawb kev pabcuam customized. Txais tos muas bulk eptifibatide hmoov cas. 188627-80-7 99% purity min rau muag ntawm no los ntawm peb lub hoobkas. Cov khoom zoo thiab tus nqi tsim nyog muaj.
Kev Tshawb Fawb Kev Tshawb Fawb ntawm Nootropics & peptide hauv Suav teb
Yinherb Lab yog lub chaw tshawb fawb kev tshaj lij hauv Suav teb, tau tsom mus rau Cov Khoom Noj Khoom Haus, Nootropics thiab Peptide raw cov ntaub ntawv tshawb fawb thiab tsim tawm hauv kev lag luam no rau ntau tshaj 10 xyoo nrog kev ruaj khov zoo thiab muaj koob npe nrov, peb tuaj yeem muab txhua qhov kev xeem batch, suav nrog COA, HPLC thiab NMR. Kuv ntseeg tias peb yuav tsum ua haujlwm zoo yav tom ntej.
Yinherb Lab High Quality Eptifibatide hmoov CAS{0}}% Purity Min
Lub Npe: Eptifibatide hmoov
CAS Nr: 188627-80-7
Molecular Formula: C₂₈H₄₃N₁₁O₉S
Molecular Luj700.78 (tsis suav nrog acetate)
Amino Acid Squence: H-Cys(1)-Asn(2)-Gly(3)-Asp(4)-Trp(5)-Pro(6)-Cys(7)-NH₂ (disulfide choj ntawm Cys1)
Qhov tshwm sim: Dawb rau tawm -dawb lyophilized hmoov
Solubility: Soluble hauv dej (Ntau dua lossis sib npaug li 50 mg / mL) thiab physiological saline, me ntsis soluble hauv methanol
Qhov ntsuas tau zoo: Ua raws li cov qauv tshuaj peptide, cov kab mob endotoxin Tsawg dua lossis sib npaug li 10 EU / mg, cov ntsiab lus dej tsawg dua lossis sib npaug li 8.0%, tsis pom cov pyrogens lossis cov hlau hnyav (tsawg dua lossis sib npaug li 10 ppm).
Purity Requirement: Feem ntau purity specification Ntau dua los yog sib npaug rau 98% (HPLC), tag nrho cov ntsiab lus impurity Tsawg dua los yog sib npaug rau 2.0%
Eptifibatide hmoov yog dab tsi?
Eptifibatide yog ib qho hluavtaws cyclic peptide antiplatelet tshuaj, feem ntau yog siv los tiv thaiv thiab kho mob plawv mob plawv (ACS) thiab cov xwm txheej ischemic, nrog rau cov txheej txheem meej ntawm kev txiav txim thiab daim ntawv thov kev kho mob.
Txoj kev tswj hwm: Intravenous txhaj (bolus) ua raws li kev txhaj tshuaj tas li.
Dosage regimen:
Loading koob tshuaj: 180 ug/kg txhaj intravenously 1-2 feeb (qhov siab tshaj plaws koob tshuaj tsawg dua los yog sib npaug rau 22.6 mg).
Kev Kho Kev Kho Mob: 2.0 ug / kg / min txuas ntxiv rau 72 teev, lossis txog thaum lub tsev kho mob tawm (txog 5 hnub) tom qab PCI.
Kev siv sib xyaw: Feem ntau ua ke nrog cov tshuaj aspirin (100–325 mg txhua hnub) thiab unfractionated heparin (intravenous infusion) txhawm rau txhim kho kev tiv thaiv kab mob thrombotic.
Eptifibatide hmoov Mechanism ntawm Kev Ua thiab Kev Ua Haujlwm Ntxiv
Nws yog ib qho kev xaiv antagonist ntawm platelet glycoprotein IIb / IIIa (GP IIb / IIIa) receptor.
Los ntawm tshwj xeeb khi rau GP IIb / IIIa receptor ntawm platelet nto, nws thaiv kev khi ntawm fibrinogen, von Willebrand yam, thiab lwm yam ligands rau receptor.
Qhov no inhibits platelet aggregation- txoj hauv kev kawg ntawm kev ua kom platelet ua kom tiav- yog li tiv thaiv kev tsim cov thrombi hauv cov hlab ntsha thiab txo qhov kev pheej hmoo ntawm cov xwm txheej ischemic.
Eptifibatide hmoov Daim ntawv thov
Mob Coronary Syndrome (ACS):
Siv rau cov neeg mob uas tsis ruaj tsis khov angina pectoris lossis tsis yog -ST- ntu nce myocardial infarction (NSTEMI), txawm tias tau txais kev cuam tshuam los ntawm percutaneous coronary intervention (PCI) lossis tau txais kev kho mob ib leeg.
Txo qhov kev pheej hmoo ntawm kev tuag, myocardial infarction, lossis refractory ischemia nyob rau lub sijhawm luv (30 hnub) los ntawm inhibiting platelet aggregation.
Percutaneous Coronary Intervention (PCI):
Kev tswj xyuas ua ntej lossis thaum lub sijhawm PCI (piv txwv li, stent implantation) txhawm rau tiv thaiv kev mob thrombotic occlusion ntawm cov hlab ntsha kho mob.
Txhim kho qhov ua tau zoo ntawm cov txheej txheem thiab txo cov teeb meem tom qab ischemic xws li myocardial infarction lossis lub hom phiaj hlab ntsha revascularization.
Lwm cov kab mob Ischemic Cardiovascular:
Tshawb nrhiav hauv kev tshawb fawb los tiv thaiv thrombosis hauv cov neeg mob uas mob myocardial infarction (STEMI) tab tom kho thrombolytic, lossis rau siab - cov neeg mob uas muaj feem cuam tshuam nrog cov hlab ntsha ntawm cov hlab ntsha bypass grafting (CABG).
Nov yog cov lus sib piv ntxaws ntxaws ntawm Eptifibatide thiab Lwm Tus GP IIb / IIIa Antagonists:
| Cov khoom sib piv | Eptifibatide | Tirofiban | Abciximab |
|---|---|---|---|
| Hom & Qauv | Synthetic cyclic peptide, xaiv GP IIb/IIIa antagonist | Synthetic non-peptide, xaiv GP IIb/IIIa antagonist | Monoclonal antibody fragment (chimeric), tsis yog - xaiv GP IIb/IIIa antagonist |
| CAS Nr | 148031-34-9 | 144494-65-5 | 108196-89-6 |
| Molecular Luj | 700.78 | 495.08 | 47615-71-4 (kwv yees) |
| Purity Specification | Ntau dua lossis sib npaug li 98% (HPLC), tag nrho cov impurities Tsawg dua lossis sib npaug li 2.0% | Ntau dua lossis sib npaug li 98% (HPLC), tag nrho cov impurities Tsawg dua lossis sib npaug li 2.0% | Ntau dua lossis sib npaug li 97% (HPLC), tag nrho cov impurities Tsawg dua lossis sib npaug li 3.0% |
| Txoj kev tswj hwm | IV bolus + nruam infusion | IV bolus + nruam infusion | IV bolus + nruam infusion |
| Core Zoo | High selectivity rau GP IIb / IIIa, sai pib / offset, tsawg immunogenicity | Ib nrab luv luv-lub neej (≈2 teev), yooj yim kho cov tshuaj, tsis tshua muaj kev pheej hmoo ntawm kev tsim tshuaj tiv thaiv | Kev sib khi zoo tshaj plaws rau GP IIb/IIIa, ntev -cov nyhuv kav ntev (ib nrab-lub neej ≈12 teev) |
| Kev txwv | Lub raum excretion- nyob ntawm, kev hloov kho ntau npaum li cas rau lub raum tsis zoo | Cov nyhuv antiplatelet tsis muaj zog dua li Abciximab, lub sijhawm ua haujlwm luv dua | Immunogenicity (kev pheej hmoo ntawm kev tsim cov tshuaj tiv thaiv kab mob), kev rov ua haujlwm ntev dua ntawm platelet muaj nuj nqi |
| Los ntshav txaus ntshai | Nruab nrab (qis dua Abciximab, siab dua Tirofiban) | Tsawg kawg ntawm peb | Siab tshaj plaws (kev pheej hmoo los ntshav hnyav xws li intracranial hemorrhage) |
| Clinical Application Scope | ACS (nrog / tsis muaj PCI), STEMI (kev tshawb fawb), PCI adjuvant | ACS (nrog / tsis muaj PCI), PCI adjuvant | Feem ntau PCI (tshwj xeeb yog cov kab mob nyuaj), refractory ACS |
| Nqe Ntau (1mg) | Hauv tsev: ~ ¥ 200-300; International: ~ $150-250 | Hauv tsev: ~ ¥ 150-250; International: $100-200 | Hauv tsev: ~ ¥ 500-800; International: $300-500 |
Cov khoom muaj feem xyuam
Tshwj xeeb hauv Semaglutide, Tirzepatide, Retatrutide, DSIP, Eptalone, Selank, Semax, Melanotan II, Thymosin alpha 1, Oxytocin, P21, Adamax, Dihexa thiab tus tub ntawm.
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Yinherb Lab nrhiav tau nyob rau hauv 2009, tau mob siab rau rau biotechnology teb rau ntau tshaj kaum xyoo. Niaj hnub no, nws tau tsim ib qho kev txhim kho kev ua haujlwm nrog "R & D + ntau lawm" ua ib qho kev sib koom ua ke. Thiab ib txwm ua raws li cov kev lag luam tseem ceeb ntawm "Quality First, Service Second, Price Third".
Peb qhov chaw nyob
No.3, Daqing rd, Hi-tech zone, Xi'an nroog, Suav teb.
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Cim npe nrov: eptifibatide hmoov cas. 188627-80-7 99% purity min, Tuam Tshoj eptifibatide hmoov cas. 188627-80-7 99% purity min manufacturers, lwm tus neeg, Hoobkas
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