Mitoquinone Mesylate Powder CAS .845959-50-4 98% Min
Lub npe Askiv: Mitoquinone Mesylate
CAS Nr .: 845959-50-4
Cov mis mos molecular: C₃₇H₄₄O₄P•CH₃SO₃
Molecular Luj: 678.80–678.81g/mol
Muaj peev xwm: 50kgs ib hlis
Source: hluavtaws
Purity (HPLC) >99.0%
Qhov chaw ntawm Keeb Kwm: Tuam Tshoj Yinherb-Lab
Packing: Raws li tus neeg siv khoom xav tau
Yam tsawg kawg nkaus Order Quantity: 1kg
Cia: Khaws rau hauv qhov chaw txias & qhuav, Khaws kom deb ntawm lub teeb muaj zog thiab cua sov rau 2 xyoos
Hauj lwm lawm
Xi'an Yinherb Bio-Tech Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm mitoquinone mesylate hmoov cas.845959-50-4 98% min hauv Suav teb, kuj txhawb kev pabcuam customized. Zoo siab txais tos mus yuav bulk mitoquinone mesylate hmoov cas.845959-50-4 98% min rau muag ntawm no los ntawm peb lub hoobkas. Cov khoom zoo thiab tus nqi tsim nyog muaj.
Kev Tshawb Fawb Kev Tshawb Fawb Txog Kev Noj Qab Haus Huv Ntxiv hauv Suav teb
Yinherb Lab yog lub chaw tshawb fawb kev tshaj lij hauv Suav teb, tau tsom mus rau Cov Khoom Noj Khoom Haus, Nootropics thiab Peptide raw cov ntaub ntawv tshawb fawb thiab tsim tawm hauv kev lag luam no rau ntau tshaj 10 xyoo nrog kev ruaj khov zoo thiab muaj koob npe nrov, peb tuaj yeem muab txhua qhov kev xeem batch, suav nrog COA, HPLC thiab NMR. Kuv ntseeg tias peb yuav tsum ua haujlwm zoo yav tom ntej.
Yinherb Lab High Quality Mitoquinone Mesylate hmoov CAS{0}}% Min
Kev txheeb xyuas cov khoom
| English npe | Mitoquinone Mesylate hmoov |
| Tshuaj npe | 10-(6'-Ubiquinonyl) decyl triphenyl phosphonium mesylate |
| Tshuaj Formula | C₃₇H₄₄O₄P•CH₃SO₃ |
| Molecular Luj | 678.80–678.81 |
| CAS Nr | 845959-50-4 |
| Qhov tshwm sim | Nws nthuav tawm raws li cov hmoov dawb / tawm -dawb crystalline hmoov |
| Purity | Cov khoom lag luam muaj nyob hauv kev lag luam feem ntau muaj purity ntau dua 99%, piv txwv li, purity ntawm cov khoom muaj npe HY - 112584 ntawm MedChemExpress nce mus txog 99.94%. |
| Yuav tsum khaws cia | Nws yuav tsum tau muab khaws cia rau hauv lub thawv kaw nruj nreem nyob rau hauv ib qho chaw txias, qhuav thiab tsaus, thiab khov cia ntawm -20℃pom zoo. |
Cov yam ntxwv tseem ceeb
Mitochondrial Targeting:TPP cation khi rau qhov tsis zoo them mitochondrial membrane muaj peev xwm, tsav kev xaiv uptake.
Antioxidant Kev Ua Haujlwm:Ubiquinone moiety scavenges superoxide (O₂⁻) thiab hydrogen peroxide (H₂O₂), inhibiting lipid peroxidation zoo dua li cov tshuaj antioxidants zoo li Trolox.
Trap1 Inhibition:Ua raws li lub zog inhibitor ntawm qog necrosis factor receptor-cov protein sib txuas 1 (Trap1, IC₅₀=0.2 μM), tswj cov metabolism hauv mitochondrial.
Mitoquinone Mesylate hmoov yog dab tsi?
Mitoquinone Mesylate (feem ntau hu ua MitoQ) yog triphenylphosphonium (TPP) -raws li mitochondria- phiaj xwm antioxidant tsim los tawm tsam oxidative puas tsuaj ntawm cellular powerhouses.
Nws cov qauv tshwj xeeb sib xyaw ua ke ntawm lipophilic TPP cation (rau mitochondrial uptake) nrog ubiquinone moiety (rau ROS scavenging), ua kom xaiv tsub zuj zuj hauv mitochondrial matrices (~ 1000x siab dua li cytoplasm).
Cov khoom no tau muab los ua cov khoom siv waxy lossis crystalline hmoov thiab tau siv dav hauv kev tshawb fawb biomedical, nrog rau cov ntawv thov hauv kev tiv thaiv - kev laus thiab kev tiv thaiv kab mob vim nws pom zoo rau tib neeg siv.
Mitoquinone Mesylate hmoov Cov txiaj ntsig thiab kev ua haujlwm
Targeted Scavening of Mitochondrial Reactive Oxygen Species (ROS): Raws li mitochondria tshwj xeeb antioxidant, nws cov triphenylphosphonium (TPP) cation tuaj yeem ua tiav 1000-fold concentration enrichment hauv mitochondrial matrix los ntawm leveraging lub peev xwm tsis zoo ntawm mitochondrial membrane, ua ncaj qha ntawm qhov chaw ntawm ROS ntau lawm. Cov quinone moiety (coenzyme Q10-derived qauv) ua tau zoo neutralizes teeb meem dawb radicals xws li superoxide anions thiab hydrogen peroxide, hloov mus rau hauv dej tsis muaj mob thiab oxygen, yog li tiv thaiv dawb radical puas rau mitochondrial DNA (mtDNA), daim nyias nyias lipids, thiab cov kab mob ua pa.
Tiv thaiv thiab kho Mitochondrial Function: Txo cov kev hloov pauv ntawm mtDNA thiab tshem tawm, tswj kev ncaj ncees ntawm mitochondrial respiratory saw (Complexes I-IV), thiab ua kom muaj txiaj ntsig zoo ntawm ATP (cellular zog tshuaj). Restores puas mitochondrial membrane muaj peev xwm (ΔΨm), thim rov qab mitochondrial dysfunction tshwm sim los ntawm oxidative kev nyuaj siab, thiab qhia txog kev kho mob tshwj xeeb tshaj yog nyob rau hauv mitochondria nyob rau hauv laus laus, raug tshuaj lom, los yog kab mob. Stabilizes mitochondrial membrane qauv, inhibits ROS-induced apoptotic pathways (xws li, cytochrome c tso, caspase activation), thiab txo cov kev tuag ntawm cov hlwb noj qab haus huv.
Tswj Redox Balance thiab Anti-Inflamation: Supplements cov reserves ntawm endogenous antioxidants xws li mitochondrial glutathione (GSH), pab txhawb lub cell tus kheej tiv thaiv kab mob. Los ntawm inhibiting NF-κB kev taw qhia txoj hauv kev kho los ntawm mitochondrial ROS, nws txo qis kev tso tawm ntawm pro-inflammatory cytokines xws li TNF- , IL-1 , thiab IL-6, alleviating chronic o nyob rau hauv cov ntaub so ntswg xws li lub paj hlwb, siab, thiab ob lub raum.
Mitoquinone Mesylate hmoov Daim ntawv thov
Kev tshawb fawb biomedical:Cov cuab yeej siv rau kev kawm mitochondrial dysfunction hauv kev laus, HIV-sociated end- kab mob hauv nruab nrog cev, neurodegeneration, thiab mob qog noj ntshav.
Pharmaceutical Development:Thawj tus neeg sib tw rau kev kho mob tsom rau mitochondrial oxidative stress (xws li, ART-txog toxicity, Alzheimer's).
Cosmeceuticals:Cov khoom xyaw hauv kev tiv thaiv- cov qauv kev laus los tiv thaiv mitochondrial ROS- ua kom tawv nqaij laus (wrinkles, poob elasticity).
Preclinical Qauv:Siv hauv vitro (cov kab ntawm tes: pancreatic acinar, MDA-MB-231) thiab hauv vivo (C57BL/6J, NSG BLT nas) rau kev siv tshuab.
Cov khoom lag luam ntsig txog
Tshwj xeeb hauv 5A-Hydroxy Laxogenin, 6-Paradol, 5-Amino-1-Mq, JBSNF-000088, BAM-15, SLU-PP-332, Urolithin A/BC, phoid-Me, 9-serphatyl, Alpha-GPC, CDP-Choline, thiab lwm yam.
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Yinherb Lab nrhiav tau nyob rau hauv 2009, tau mob siab rau rau biotechnology teb rau ntau tshaj kaum xyoo. Niaj hnub no, nws tau tsim ib qho kev txhim kho kev ua haujlwm nrog "R & D + ntau lawm" ua ib qho kev sib koom ua ke. Thiab ib txwm ua raws li cov kev lag luam tseem ceeb ntawm "Quality First, Service Second, Price Third".
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